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Animal-model studies have characterized effects on wound closure rates, on the histological features of healing wounds, on collagen deposition and organization in healing tissue, and on the broader cellular and molecular processes of repair

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We also keep an eye on blood sugar and insulin resistance, cholesterol and blood pressure, liver markers, energy, sleep, and mood

Some patients who achieve initial remission may see diabetes return years later, particularly with weight regain

What this means for clinical research: Clinical timelines are no longer shaped by execution alone